Pvp K30 CAS9003-39-8 Polyvinylpyrrolidone High Quality Pharmaceutical Chemical

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Application of Polyvinylpyrrolidone pvp in medicine and health：

PVP has the longest history of application in medicine and health, and it is by far the most widely used field. The PVP product used as a plasma solubilizer during World War II is "Periston". It is an isotonic saline composed of 3.5% PVP. It has a significant effect on shock caused by acute massive blood loss or burns, and has nothing to do with the blood type of the recipient.

The preparation method of "Periston" is as follows:

Add 20% PVP solution (mass) to 70L of distilled water at 50°C, then add NaCl, KCl, CaCl₂·6H₂O, MgCl₂·6H₂O in sequence to dissolve completely, dissolve NaHCO₃ in 6-7L of distilled water, and then slowly add To 1mol/L hydrochloric acid, when the bubbling (CO₂) stops, add this solution to the solution of PVP and hydrochloride, and then dilute the above mixture with distilled water to a preparation solution with a PVP concentration of 3.5%, and finally The preparation solution is filtered with a steam-sterilized filter while it is hot (the operation process and the instruments used must be performed under sterile conditions). Sterilize the bottle at 105-120°C and store it at 35°C for three weeks. If no solid matter is deposited, it can be used for clinical use.

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