Povidone K30 Use As Binder

Ulanqab Kema New Material Co., Ltd. is one of the most experienced manufacturers and suppliers of povidone k30 use as binder in China. Please rest assured to wholesale high quality povidone k30 use as binder made in China here from our factory. If you have any enquiry about free sample, please feel free to email us.

What is the binder?

Binders hold the ingredients in a tablet together. Binders ensure that tablets and granules can be formed with required mechanical strength, and give volume to low active dose tablets.

Application:

（1）Medicine & Health:

PVP has excellent physiological inertia, does not participate in human metabolism, and has excellent biocompatibility, and does not cause any irritation to the skin, mucous membranes, eyes, etc. From a biological point of view, the molecular structure of PVP is similar to the structure of a simple protein model, and even its water-soluble ability to cooperate with certain small molecules and can be used by certain protein precipitants, ammonium sulfate, The precipitation of trichloroacetic acid, tannins and phenols is also compatible with protein. As a result, PVP is widely used as an excipient for pharmaceutical preparations. Specific applications are as follows: ①Used as a binder for preparations ②Co-precipitating agent ③Used as a cosolvent or crystal formation inhibitor in injection ④Coating or film-forming agent Action time of the drug ⑥ Artificial vitreous and cornea ⑦ Surgical bandage. In addition, PVP can also be used as a colorant and X-ray contrast agent; it can be used in various dosage forms such as tablets, granules, liquids, etc. It has the functions of detoxification, hemostasis, increasing the dissolved concentration, preventing peritoneal adhesions, and promoting erythrocyte sedimentation rate.

（2）Food Processing:

PVP itself is not carcinogenic, has good food safety, and can form complexes with specific polyphenol compounds (such as tannins). In food processing, it is mainly used as a clarifying agent and stabilizer for food such as beer, fruit juice, and wine.

（3）Daily cosmetics:

In the consumption structure of PVP, the cosmetics industry in developed countries accounts for 30% to 50%, and my country accounts for 70% to 80%. Because PVP has extremely low toxicity and physiological inertia, it has no irritation to the skin and eyes and has long-term use records in the medical field, so it is safe to use in cosmetics. In daily cosmetics, PVP and copolymers have good dispersibility and film-forming properties. PVP can protect colloids in emulsions. It can be used in fatty and non-fat pastes, as styling liquid, hair spray and rub Silk setting agent, sunscreen for hair conditioner, foam stabilizer for shampoo, wave setting agent, and dispersant and affinity agent in hair dye. Adding PVP to vanishing cream, sunscreen, and depilatory can enhance the moisturizing and lubricating effect.

(4) Coating or film forming agent

Adding PVPK25 and K30 to the drug film coating can not only increase the adhesion of the coating to the drug base due to the high cohesive force of PVP, but also increase the stability of the coating suspension due to its excellent dispersibility and avoid pigmentation. Reunion and migration. The excellent film-forming properties of PVP can also prevent fine cracks on the coating surface during drying. However, it should be noted that, due to its hygroscopicity and stickiness in the air, soluble PVP cannot be used as a single film-forming agent, but should be used in combination with cellulose derivatives, methacrylic acid, resin and other film-forming agents. Alcohol-containing pigment dispersions can be prepared with shellac and PVP, especially in spray and fluidized bed coating equipment to obtain uniform coatings, and improve the dissolution rate of the film-forming agent in water.

(5) Capsule glidant

During the filling process of the capsule filling machine, if you encounter light powder with a small specific volume, you can add 1 to 2% PVP ethanol solution to help granulation and improve the flow ability. In foreign countries, PVP is used as a glidant in hard gelatin pills such as cyclomandelate, disopyramide, hydroxyethyl pyridine, and ethyl papaverine long-acting capsules. There are few reports on the application of PVP to soft capsules. The Japanese Chemical Pharmaceutical Company added a small amount of PVP (2%) as a dispersant when preparing nifedipine soft pills.

About Us:

Ulanqab Kema New Material Co., Ltd has an advantageous geographical location, close to the Chinese Capital Economic Zone, 11 prefecture-level cities including Beijing, Tianjin, Hebei Province, and two municipalities directly under the control of the province. It is also relatively close to the main raw material producing areas, and the transportation cost is relatively low. Calcium carbide is the main product of the parent company Baiyan Lake Chemical, and it plans to produce BDO and γ-butyrolactone, so the supply and transportation of raw materials in the future have guarantees and advantages.

At present, the company has steadily improved product quality through continuous R&D investment and continuous process technology optimization. And has obtained a number of NVP, PVP production patents, the quality of pharmaceutical PVP K series products, PVP/VA copolymers, and PVP iodine products have reached the current technical requirements of major European countries. Over the past three years, all the employees of the company have carried forward the enterprise spirit of “Dare to think, adept at work and strive for perfection”, to seek technological breakthroughs and management upgrades, with product quality improved steadily and sales market expanded continuously. 

The company has obtained ISO9001 quality management system certificate, ISO45001 occupational health and safety management system certificate, ISO14001 environmental system certificate, EU REACH certificate, Turkish KKDIK certificate, foreign trade operator certificate, high-tech enterprise certificate, and a number of patent certificates, and it even completed the filing registration, listed on the Inner Mongolia Equity Exchange Center Science and Technology Innovation Board, established"Povidone New Material R&D Center" with the Inner Mongolia University of Technology and cooperated with Tianjin University on the R&D project of "Technology Development and Industrialization of NVP Preparation of Monomer for High Purity PVP".

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