Usages of PVP
As a synthetic water-soluble polymer compound, PVP has the general properties of water-soluble polymer compounds, such as colloid protection, film-forming, cohesiveness, hygroscopicity, solubilization, or agglomeration. People pay attention to its excellent solubility and physiological compatibility. Among synthetic polymers, it is rare that PVP is soluble in water and most organic solvents, with low toxicity and good physiological compatibility, especially in medicine, food, and cosmetics, which are closely related to people's health. In the field, with the reduction of the price of its raw material butyrolactone, it will show a good prospect for its development. The following is a specific introduction to its application areas:
1. Medicine & Health
PVP has excellent physiological inertia, does not participate in human metabolism, and has excellent biocompatibility, and does not cause any irritation to the skin, mucous membranes, and eyes. From a biological point of view, the molecular structure of PVP is similar to that of a simple protein model, even its water-solubility, its ability to complex certain small molecules and its ability to be inhibited by certain protein precipitants The properties of ammonium sulfate, tri-occurrence of restricted words, precipitation of tannins and phenols are also compatible with proteins. So that PVP is widely used as an adjuvant for pharmaceutical preparations, the specific applications are as follows: ① as a binder for preparations ② as a co-precipitant ③ as a cosolvent or crystallization inhibitor in injections ④ coating or film-forming agent ⑤ The controlled release of retarder and sustained-release drug can prolong the action time of the drug. ⑥ Artificial vitreous and cornea ⑦ Surgical bandage ⑧ PVP iodine disinfectant. In addition, PVP can also be used as a colorant and X-ray contrast agent; it can be used in various dosage forms such as tablets, granules, and water preparations, and has the functions of detoxification, hemostasis, increasing dissolved concentration, preventing peritoneal adhesion, and promoting erythrocyte sedimentation rate.
2. Food Processing
PVP itself is not carcinogenic, has good food safety, and can form complexes with specific polyphenolic compounds (such as tannins).